Turn Gross-to-Net Complexity into Confident, Audit-Ready Decisions

Managed Market Finance breaks down because manufacturers are forced to manage thousands of complex contracts, claims, and rebates with systems never designed for transaction-level accuracy, automation, or control.


Keystone AI combines RAIN™ transaction-level encoding with prediction and economics-aware decisioning to deliver accurate, audit-ready gross-to-net control across claims, contracts, chargebacks, and rebates.
By learning directly from real operational events, Keystone AI outperforms aggregate and rule-based systems in environments defined by contractual complexity, retroactivity, and compliance risk—reducing leakage and manual effort.
Designed to layer alongside our customer's existing systems of record, Keystone integrates into existing MMF workflows to automate safe decisions, prioritize high-impact exceptions, and scale control without rip-and-replace.


Pharmaceutical manufacturers face extreme contractual complexity across payers, PBMs, wholesalers, and government programs. Traditional revenue and gross-to-net systems break down precisely where risk is highest — at the claim × contract × customer level—driving leakage, growing exceptions, and compliance exposure.
Keystone’s Managed Market Finance solution operates directly on transaction-level claims, chargebacks, and rebates. By encoding contract terms, eligibility, and real-world events, Keystone delivers auditable, economics-aware decisioning that scales control without manual intervention.
Optimizations:
· Chargeback and rebate adjudication & prioritization
· Gross-to-net forecasting & accrual accuracy (payer × channel × program)
· Exception triage based on financial and compliance risk
· Contract compliance, eligibility validation, and audit readiness


Medical device manufacturers operate with complex, customer-specific pricing across GPOs, IDNs, distributors, and providers. Traditional revenue and deduction systems break down where complexity is highest—at the invoice × contract × customer level—driving chargeback disputes, margin leakage, and slow close cycles.
Keystone’s Managed Market Finance solution reconciles distributor chargebacks, rebates, and eligibility at the transaction level. By encoding contract terms, pricing hierarchies, and customer relationships, Keystone enables accurate adjudication, automated exception handling, and audit-ready revenue control at scale.
Optimizations:
• Distributor chargeback validation and dispute resolution
• Contract pricing and eligibility enforcement (GPO × IDN × facility)
• Deduction accruals and net revenue accuracy
• Exception prioritization based on margin and risk


Unlocked $20M+ in incremental free cash flow by deploying Foundation Forecasting™ model that improved fine-grain forecast accuracy which drove inventory optimization.
Generated $19M+ in incremental purchases by deploying Causal Attribution & Downstream Impact models that enabled marketing team to dynamically optimize product selection, promotions, and nurture based on audience.
Reduced stockout rate from previous year by 75% by deploying Foundation Forecasting™ model and control tower that improved forecast accuracy and inventory management.
Enterprises are at an inflection point. Operational and technology-driven silos hinder performance. Fragmented data, legacy Enterprise Resource Planning systems, and non-scientific decision-making has left businesses struggling to keep pace — case in point we have witnessed a 30% attrition in the Fortune 500 over the past decade.
In global supply chains, demand planners are not able to perform high-grain forecasts across SKUs, markets and seasons. As a result, inventory managers make stocking decisions based on low-fidelity insights. On commercial teams, marketers struggle to understand which promotional, pricing and media decisions will have the greatest impact. In finance, we see FP&A struggle to stitch cross-functional forecast together. Despite their interdependence, the main operating functions of a business remain disconnected.
The AI revolution changes everything. Our mission is to help our customers transform into Deep Enterprises. We define the "Deep Enterprise" as a company that embeds neural network-based AI into the core of it's decision-making infrastructure. This is the natural next step from digital transformation and it promises operational improvement, optimized financial performance and a balance of immediate results and long-term value creation.
If your enterprise is in the automotive, consumer packaged goods, financial services, healthcare & pharmaceuticals, life sciences, manufacturing & industrial goods, hospitality, or telecommunications sectors, contact us to learn more.